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Pancreatic Cancer
Specialized expertise with innovative, low-dose combination regimens for one of the most difficult cancers to treat.
At Hirschfeld Oncology, exceptional care is never the work of one person — it’s the strength of a dedicated team.
Led by Dr. Azriel Hirschfeld, our physicians, nurses, and medical staff work together to design treatment plans grounded in science, compassion, and experience. Each team member plays a vital role — guiding patients through every step and ensuring care that’s coordinated, precise, and hopeful.
Low-Dose Multi-Drug Combinations
By combining chemotherapy drugs at lower doses, Dr. Hirschfeld reduces side effects while maximizing the synergy between medicines to fight cancers more effectively.
Standard of Care—With an Expanded Therapeutic Lens
Our foundation is standard-of-care chemotherapy, guided by well-established clinical evidence and outcomes data.Where appropriate, we build upon this foundation by integrating targeted therapies and refined dosing strategies to enhance effectiveness while maintaining tolerability.
Beyond Institutional Treatment Constraints
Because we are not limited by large-institution protocols, we can thoughtfully apply emerging Phase II clinical data and evolving treatment strategies—when supported by science—to offer options beyond conventional care pathways.
Genomic profiling
Each tumor’s unique genetic profile is analyzed, allowing therapies to be precisely matched to the cancer’s biology for greater accuracy and impact.
Data-Driven Off-Label Use
When evidence strongly supports benefit, FDA-approved drugs are used off-label, giving patients earlier access to promising treatments beyond standard protocols.
Low-dose chemotherapy. Immunotherapy. Personalized treatment strategies. A team that truly understands complex cancer battles.
Meet with Dr. Azriel Hirschfeld to discuss what options are available to you.
The immune system is made of white blood cells, organs, and lymph tissues. Immunotherapy activates these components, making it a powerful form of biological therapy against cancer.
Because drugs act at different stages of the cell cycle, combining them increases the chance that all cancer cells will be eliminated. This strategy helps overcome resistance and improves patient outcomes.
With experience and compassion, we understand the challenges you face. We work to make the treatment process as smooth, easy, and comfortable as possible.
These health insights highlight the impact of innovative treatments and compassionate care. They offer hope, perspective, and connection for those facing cancer today.
Lower toxicity, better tolerance
Multi-drug synergy against resistant cancer
Enhanced quality of life during treatment
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One of Dr. Hirschfeld’s signature methods is the use of low-dose combination chemotherapy. By safely combining multiple drugs at reduced doses, he harnesses their synergy to target resistant cancers more effectively — achieving strong results with fewer side effects and bringing new hope to patients.
Specialized expertise with innovative, low-dose combination regimens for one of the most difficult cancers to treat.
Advanced strategies for rare and aggressive bile duct cancers, offering options beyond standard care.
Personalized treatment plans that integrate proven therapies with cutting-edge approaches when resistance develops.
Tailored regimens designed to improve outcomes and quality of life in complex stomach cancer cases.
While Hirschfeld Oncology specializes in gastrointestinal cancers, Dr. Hirschfeld’s methodology has also shown success in treating select cases of other aggressive or treatment-resistant cancers.
Women’s Cancers Research
In vitro disease models predicted advantages for use of 1/2-1/4 standard cytotoxic doses and selection of drugs each of which simultaneously interact with multiple drugs.
Anticancer research
Targeted therapy added to cores of previously failed drugs has similarly produced responses of refractory pancreatic cancer.
Women’s Cancers Research
The use of Bevacizumab (Bev) for ovarian cancer (OC) has been impeded by adverse events (AEs), long maintenance therapy (T) and tumor rebound. Eligibility, requirements and limits, as well as ideal time(s) and length of use remain unknowns. Drug interactions and algorithms offer testable solutions.
Dr. Azriel Hirschfeld is a servant to his profession--a close listener, smart as a whip, patient, kind, informed and above all a learner. Have been to a swarm of doctors on our journey and not one measures up to this doctor's professionalism and giftedness. He is a rare find.
Cristina M
Happy Patient
BEST ONCOLOGIST in the world 🙏🏻 I am forever thankful to have found him . Dr. Hirshfeld is very patient and listens . Unlike other places I am NOT just a number to him , he cares and it shows .
Sima Homapour
Happy Patient
Dr. Hirschfeld was incredibly knowledgeable and was so easy to talk to. He acted like I was his only patient today, spending so much time with me with no distractions. And his “bedside manner” is amazing.
Jaime Kaplan
Happy Patient
I am more than happy, this being my first time with the doctor. I felt more than good. I recommend that you go and treat yourself with the doctor. The place is clean and pleasant, she treats you with great respect and is very kind. I liked it a lot, and she helps with whatever problem I have. Thank you
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Gladys Luyando
Happy Patient
Leah and Francine are super professional, they know exactly what they are doing, they know each and every patient personally. They are the best support team you could ask for when you go through a rough time and being diagnosed.
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Tiffany Bargig
Happy Patient
Dr. Hirschfeld took on my problem and made it his problem. We started chemo therapy on second week and many other procedures like frequent shots to increase white blood cells, imuno therapy every other week, constant blood work to test for prognosis and many other procedures that make you feel that your are being taken care of by right people when one is at the most vulnerable position.
Grisha Abayev
Happy Patient
February 5, 2026
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